Long-Term follow-up of AdVanceTMXP male sling for post prostatectomy incontinence.

Our objective was to evaluate the long-term efficacy of AdVanceTMXP male sling in the treatment of post radical prostatectomy urinary incontinence.

86 patients underwent male sling surgery at our center between 2010 and 2017. Data were collected in 2022 from electronic medical records, telephone interviews, standardized and validated questionnaires, including the ICIQ-SF, PGI-I, and Pad Test.

Among 86 patients, 16 deceased prior 2022, 16 had no efficacy at the one-month post-operative evaluation, and 4 were lost to follow-up. Adverse events occurred in 25 cases. With a median follow-up of 100 months, efficacy at the end of follow up was observed in 41/86 (48%) patients. Among the 50 patients who had initial postoperative efficacy, 32 (64%) maintained efficacy at the end of follow-up. Loss of efficacy in the remaining 18 patients occurred with a median of 36 months. Quality of life was significantly decreased in the non-effective group of patients. A history of radiotherapy, a history of operated urethral stricture, severe preoperative urinary incontinence, and age ≥70 years were significantly associated with the loss of efficacy in univariate analysis. In multivariate analysis, only severe preoperative urinary incontinence remained significantly associated with loss of efficacy.

With a median follow-up of 100 months, efficacy at the end of follow up was observed in almost half of all patients.

The French journal of urology. 2025 Mar 12 [Epub ahead of print]

Victoria Ducos, Romain Pelette, Victor Lescure, Yannis Brakbi, Florent Beaujouan, Guillaume Charron, Zaccharia Hammoudi, Marie Chicaud, Mathieu Lefief, Jules Boudot, Xavier Plainard, Aurélien Descazeaud

Department of urology, Limoges University Hospital, Limoges, France. Electronic address: ., Department of urology, Limoges University Hospital, Limoges, France.