Peyronie's disease (PD) is a connective tissue disorder of the penis that causes pain, curvature, and erectile dysfunction. Methods: A prospective study was conducted on 112 patients treated with ESWT. Each received three sessions of 3,000 shockwaves at 0.11-0.17 mJ/mm2. Pain, curvature, and erectile function were assessed.
Pain relief occurred in 90% of patients (mean VAS reduction: 3, p<0.00001); 57.1% had curvature improvement (mean 30°, p<0.001); 26.2% of ED patients improved ≥ 4 points in IIEF.
ESWT appears safe and effective in improving pain and curvature in PD patients.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2026 Mar 02 [Epub ahead of print]
Giuseppe Saitta, Riccardo Trovato, Vincenzo Striano, Simone Di Salvatore, Giuseppe Di Paola, Andrea Simone Ceresoli, Franco Anacleto Mantovani, Attilio Luigi Meazza, Mauro Seveso
Istituto Clinico Città Studi, Milan., Humanitas Clinical Research Hospital, Pieve Emanuele (MI).