The prevalence of nephrolithiasis has been increasing in recent years, affecting appro-ximately 10% and 15% of the population. Kidney stone disease is associated with syste-mic comorbidities such as cardiovascular dis-ease, diabetes mellitus, and obesity. The first Nephrolithiasis Guideline by the Brazilian Society of Nephrology was published in 2002, and since then, the accumulation of new clinical studies and guidelines has justified a review of the subject. This updated document, prepared by the Nephrolithiasis Committee of the Brazilian Society of Nephrology, reflects the advances in the management of patients with kidney stones. The guideline aims to provide recommendations for the diagnosis, prevention, and treatment of nephrolithiasis, based on the best available evidence. Topics covered include clinical evaluation, laboratory and imaging tests, as well as dietary and pharmacological interventions, and follow-up strategies.
Jornal brasileiro de nefrologia. 2025 Dec [Epub]
Mauricio de Carvalho, Ana Cristina Carvalho de Matos, Daniel Rinaldi Dos Santos, Daniela Veit Barreto, Fellype Carvalho Barreto, Fernanda Guedes Rodrigues, Igor Gouveia Pietrobom, Lucas Gobetti da Luz, Natasha Silva Constancio, Samirah Abreu Gomes, Ita Pfeferman Heilberg
Universidade Federal do Paraná, Hospital de Clínicas, Curitiba, PR, Brazil., Universidade Federal de São Paulo, Disciplina de Nefrologia, Escola Paulista de Medicina, São Paulo, SP, Brazil., Faculdade de Medicina do ABC, Santo André, SP, Brazil., Universidade Federal de São Paulo, Pós-Graduação em Nutrição, São Paulo, SP, Brazil., Hospital Moinhos de Vento, Departamento de Nefrologia, Porto Alegre, RS, Brazil., Hospital Regional Alto Vale e Associação Renal Vida, Rio do Sul, SC, Brazil., Universidade de São Paulo, Faculdade de Medicina, São Paulo, SP, Brazil.