The current systematic review aims to summarize the existing data on intraoperative use of artificial intelligence (AI) during endoscopic lithotripsy in order to assess which particular applications are feasible and have prospects of wide implementation into practice.
The review included studies where adult patients with urolithiasis underwent any type of endoscopic lithotripsy with intraoperative application of AI. Preclinical trials (on animals or phantom kidneys) focusing on modelling endoscopic lithotripsy and AI application for this procedure were also considered.
Six articles were included. The primary AI applications can be categorized into three domains: intraoperative navigation; tissue and stone differentiation; stone classification according to chemical composition. AI enabled reconstruction of the 3D map of endoscope movement with an accuracy of 0.6 mm and stone size measurement with an accuracy of 0.06 mm, differentiating between laser interactions with stone and tissue and differentiating between 4 common stone types (calcium oxalate monohydrate, calcium oxalate dihydrate, uric acid, and brushite). However, most of the data was obtained in experimental setups, rendering AI performance in real clinical settings still unclear.
This review found that AI technologies show promise in endoscopic lithotripsy, with current systems already capable of performing accurate tissue and stone segmentation, intraoperative navigation, and stone classification, although at the moment still there is no solid clinical background, and our conclusions are predominantly based on experimental studies. Currently AI clinical utility is still questionable due to lack of studies, especially validated ones. Continued development and clinical adoption are needed to further improve urological surgery outcomes.
World journal of urology. 2025 Oct 30*** epublish ***
Andrey Morozov, Igor Matkovskiy, Bhaskar Somani, Jack Baniel, Olivier Traxer, David Lifshitz, Stanislav Ali, Yaron Erlich, Shay Golan, Dmitry Pushkar, Giovanni E Cacciamani, Vineet Gauhar, Dmitry Enikeev
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia., N. V. Sklifosovskiy Institute of Clinical Medicine, Sechenov University, Moscow, Russia., Department of Urology, University Hospital Southampton NHS Trust, Southampton, UK., Rabin Medical Center, Petah Tikva, Israel., Hôpitaux Universitaires Paris-Est, AP-HP, Université Pierre et Marie Curie Paris, Paris, France., Urology Department, Moscow State University of Medicine and Dentistry, Moscow, Russia., USC Institute of Urology and Catherine & Joseph Aresty Department of Urology, Keck School of Medicine, Los Angeles, USA., Ng Teng Fong General Hospital, NUH, Singapore, Singapore., Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia. .
PubMed http://www.ncbi.nlm.nih.gov/pubmed/41165843