Penile & Urethral Cancers
Danish National Penile Cancer Database, DaPeCa-Data: Characteristics, Management, and Survival 2000-2025 - Beyond the Abstract
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Single-cell immunoprofiling reveals a dysfunctional-like immune microenvironment and malignant phenotype in aging penile squamous cell carcinoma.
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Penile squamous cell carcinoma (PSCC) can affect men of any age, but we know little about the differences between non-old and old patients with PSCC, which severely limits the precise diagnosis and treatment of PSCC.
Comparison of PET imaging of [18F]F-FAPI and [18F]F-FDG for diagnosis of suspected lymph node metastases in penile squamous cell carcinoma: a prospective pilot study.
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To evaluate the potential value of [18F]F-FAPI PET/CT for detecting inguinal lymph node (ILN) metastases in locally advanced penile squamous cell carcinoma (PSCC) and to compare the results with those of [18F]F-FDG PET/CT.
Surgical Margin Status and Minimal Margin Width in Penile Squamous Cell Carcinoma: Local Recurrence and Survival Outcomes in a Single-Centre Cohort.
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Background/Objectives: Optimal surgical margin management in penile squamous cell carcinoma remains debated because organ-preserving surgery must balance oncological control with functional preservation.
Neoadjuvant Treatment for Penile Cancer: A Systematic Review of Contemporary Evidence.
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Background/Objectives: Penile squamous cell carcinoma (SCC) is a rare but aggressive malignancy in which survival declines sharply once regional lymph nodes are involved. Neoadjuvant therapy is recommended for clinically node-positive disease to improve resectability and address micro-metastatic spread; however, the supporting evidence remains limited.
Prognostic Significance of Pretreatment Blood-Based Biomarkers in Penile Cancer: A Multicenter Retrospective Study in Japan.
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Penile cancer is a rare malignancy, and multicenter data evaluating prognostic biomarkers in the Japanese population are limited. This study aimed to assess the prognostic significance of pretreatment blood-based biomarkers in patients with penile cancer.
Histological and Molecular Evaluation of HPV in Primary Tumors and Lymph Node Metastases of Penile Cancer.
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Penile squamous cell carcinoma is an uncommon neoplasm that arises via two carcinogenic pathways, one linked to HPV infection and the other to chronic inflammation and p53 alterations.
We assessed the distribution of HPV genotypes in penile tumors and subsequent inguinal metastases in a cohort of 343 patients, analyzing their concordance with p16 stain and histological subtype, as well as the predictive significance of HPV tumor status and the immunohistochemical expression of p16 and p53 in inguinal lymph node metastasis (ILNM).
Quality and readability of online penile-cancer information: a Cross-Sectional Web Study.
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Penile cancer is rare, and patients increasingly rely on the internet for health information. On April 1, 2025, we conducted a cross-sectional evaluation of the quality and readability of the top 100 Google search results; 71 websites were included in the analysis.
B7-H3 (CD276) as Target for T Cell-Based Bispecific Antibody Therapy of Penile Cancer.
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Metastatic or locally advanced penile cancer (PeCa) has limited systemic treatment options and a 5-year survival rate of ~10% in metastatic disease. Using the in vitro and ex vivo models we preclinically assessed CC-3, a B7-H3xCD3 bispecific antibody (bsAb) currently in a Phase I basket trial (NCT05999396).
Impact of treatment volume on outcomes for patients with penile cancer at relatively low-volume centers in Japan.
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To investigate whether there are differences in treatment approaches, including complications according to the volume of treatment experience for penile cancer, and whether such differences affect patient prognosis.