PURPOSE: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA).
MATERIALS AND METHODS: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors.
RESULTS: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m(2), respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 ml="" min="" at="" postoperative="" 12="" months="" p="" 0="" 001="" and="" from="" the="" multiple="multiple" linear="" regression="" equation="" predicted="" probability="" logistic="" we="" could="" calculate="" for="" ratio="" of="" living="" donor="" kidney="" volume="" to="" recipient="" bsa="" on="" graft="" function=""> CONCLUSIONS: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.
Written by:
Lee CK1, Yoon YE1, Choi KH1, Yang SC1, Lee JS2, Joo DJ3, Huh KH3, Kim YS3, Han WK1 Are you the author?
1Department of Urology, Urological Science Institute, Yonsei University Health System, Seoul, Korea. 2Department of Urology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. 3Department of Surgery, The Research Institute for Transplantation, Yonsei University Health System, Seoul, Korea.
Reference: Korean J Urol. 2013 Dec;54(12):870-5 (Epub 2013 Dec 10)
doi: 10.4111/kju.2013.54.12.870
PubMed Abstract
PMID: 24363870
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